The study of signatures of aging in terms of genomic biomarkers can be uniquely helpful in understanding the mechanisms of aging and developing models to accurately predict the age. Prior studies have employed gene expression and DNA methylation data aiming at accurate prediction of age. In this line, we propose a new framework for human age estimation using information from human dermal fibroblast gene expression data. First, we propose a new spatial representation as well as a data augmentation approach for gene expression data. Next in order to predict the age, we design an architecture of neural network and apply it to this new representation of the original and augmented data, as an ensemble classification approach. Our experimental results suggest the superiority of the proposed framework over state-of-the-art age estimation methods using DNA methylation and gene expression data.

This work provides a unified framework for addressing the problem of visual supervised domain adaptation and generalization with deep models. The main idea is to exploit the Siamese architecture to learn an embedding subspace that is discriminative, and where mapped visual domains are semantically aligned and yet maximally separated. The supervised setting becomes attractive especially when only few target data samples need to be labeled. In this scenario, alignment and separation of semantic probability distributions is difficult because of the lack of data. We found that by reverting to point-wise surrogates of distribution distances and similarities provides an effective solution. In addition, the approach has a high "speed" of adaptation, which requires an extremely low number of labeled target training samples, even one per category can be effective. The approach is extended to domain generalization. For both applications the experiments show very promising results.

The pandemic of these very recent years has led to a dramatic increase in people wearing protective masks in public venues. This poses obvious challenges to the pervasive use of face recognition technology that now is suffering a decline in performance. One way to address the problem is to revert to face recovery methods as a preprocessing step. Current approaches to face reconstruction and manipulation leverage the ability to model the face manifold, but tend to be generic. We introduce a method that is specific for the recovery of the face image from an image of the same individual wearing a mask. We do so by designing a specialized GAN inversion method, based on an appropriate set of losses for learning an unmasking encoder. With extensive experiments, we show that the approach is effective at unmasking face images. In addition, we also show that the identity information is preserved sufficiently well to improve face verification performance based on several face recognition benchmark datasets.

我们介绍了StreamNet，这是一种自动编码器体系结构，用于分析大量白质流线的高度异质几何形状。该提出的框架利用了Wasserstein-1度量的几何形状赋值特性，以实现整个流线束的直接编码和重建。我们表明，该模型不仅可以准确捕获人群中流线的分布结构，而且还能够在真实和合成流线之间实现出色的重建性能。使用最新的ART捆绑包比较度量标准，对40个健康对照的T1加权扩散成像产生的白质流线评估了实验模型性能。

大型语言模型已经证明了能够在自然语言和编程语言文本上进行条件和生成的能力。这样的模型打开了多语言代码生成的可能性：代码生成模型是否可以将知识从一种语言推广到另一种语言？尽管当代代码生成模型可以生成语义上正确的Python代码，但对它们使用其他语言的能力知之甚少。我们通过提出Multipl-E来促进该主题的探索，这是自然语言到代码生成的第一个多语言平行基准。 Multipl-E扩展了HumaneVal基准（Chen等，2021），以支持另外18种编程语言，涵盖了一系列编程范式和受欢迎程度。我们在Multipl-E：Codex和Incoder上评估了两个最先进的代码生成模型。我们发现，在几种语言上，法典匹配，甚至超过了其在Python上的性能。在多型E中表示的编程语言范围使我们能够探索语言频率和语言功能对模型性能的影响。最后，将代码生成基准分配给新编程语言的多重方法既可扩展又可扩展。我们描述了一种通用方法，可以轻松地增加对新基准和语言的支持。

例如，对年龄相关基因的调查对于多种目的具有重要意义，例如，改善了我们对老化机制，增加预期寿命，年龄预测和其他医疗保健应用的理解。在他的作品中，从一组27,142个基因开始，我们通过应用无监督和半监督的人类皮肤成纤维细胞基因表达数据来鉴定与老化相关的基因的信息理论框架。首先，我们使用无监督的学习和应用信息 - 理论措施来识别转录组数据中基因表达值的有效表示的关键特征。使用所识别的功能，我们在数据上执行群集。最后，我们使用不同距离措施对群集进行半监督学习，以鉴定可能与老化有关的新基因。无监督和半监督方法的性能评估显示了框架的有效性。

Transformers do not scale very well to long sequence lengths largely because of quadratic self-attention complexity. In the recent months, a wide spectrum of efficient, fast Transformers have been proposed to tackle this problem, more often than not claiming superior or comparable model quality to vanilla Transformer models. To this date, there is no well-established consensus on how to evaluate this class of models. Moreover, inconsistent benchmarking on a wide spectrum of tasks and datasets makes it difficult to assess relative model quality amongst many models. This paper proposes a systematic and unified benchmark, Long-Range Arena, specifically focused on evaluating model quality under long-context scenarios. Our benchmark is a suite of tasks consisting of sequences ranging from 1K to 16K tokens, encompassing a wide range of data types and modalities such as text, natural, synthetic images, and mathematical expressions requiring similarity, structural, and visual-spatial reasoning. We systematically evaluate ten well-established long-range Transformer models (Reformers, Linformers, Linear Transformers, Sinkhorn Transformers, Performers, Synthesizers, Sparse Transformers, and Longformers) on our newly proposed benchmark suite. Long-Range Arena paves the way towards better understanding this class of efficient Transformer models, facilitates more research in this direction, and presents new challenging tasks to tackle. Our benchmark code will be released at https://github.com/google-research/long-range-arena.

Variational inference uses optimization, rather than integration, to approximate the marginal likelihood, and thereby the posterior, in a Bayesian model. Thanks to advances in computational scalability made in the last decade, variational inference is now the preferred choice for many high-dimensional models and large datasets. This tutorial introduces variational inference from the parametric perspective that dominates these recent developments, in contrast to the mean-field perspective commonly found in other introductory texts.

Knowledge graphs (KG) have served as the key component of various natural language processing applications. Commonsense knowledge graphs (CKG) are a special type of KG, where entities and relations are composed of free-form text. However, previous works in KG completion and CKG completion suffer from long-tail relations and newly-added relations which do not have many know triples for training. In light of this, few-shot KG completion (FKGC), which requires the strengths of graph representation learning and few-shot learning, has been proposed to challenge the problem of limited annotated data. In this paper, we comprehensively survey previous attempts on such tasks in the form of a series of methods and applications. Specifically, we first introduce FKGC challenges, commonly used KGs, and CKGs. Then we systematically categorize and summarize existing works in terms of the type of KGs and the methods. Finally, we present applications of FKGC models on prediction tasks in different areas and share our thoughts on future research directions of FKGC.

Few Shot Instance Segmentation (FSIS) requires models to detect and segment novel classes with limited several support examples. In this work, we explore a simple yet unified solution for FSIS as well as its incremental variants, and introduce a new framework named Reference Twice (RefT) to fully explore the relationship between support/query features based on a Transformer-like framework. Our key insights are two folds: Firstly, with the aid of support masks, we can generate dynamic class centers more appropriately to re-weight query features. Secondly, we find that support object queries have already encoded key factors after base training. In this way, the query features can be enhanced twice from two aspects, i.e., feature-level and instance-level. In particular, we firstly design a mask-based dynamic weighting module to enhance support features and then propose to link object queries for better calibration via cross-attention. After the above steps, the novel classes can be improved significantly over our strong baseline. Additionally, our new framework can be easily extended to incremental FSIS with minor modification. When benchmarking results on the COCO dataset for FSIS, gFSIS, and iFSIS settings, our method achieves a competitive performance compared to existing approaches across different shots, e.g., we boost nAP by noticeable +8.2/+9.4 over the current state-of-the-art FSIS method for 10/30-shot. We further demonstrate the superiority of our approach on Few Shot Object Detection. Code and model will be available.